Arthrosamid® is an intra-articular polyacrylamide hydrogel injection (iPAAG) for the symptomatic treatment of knee osteoarthritis. Once injected into the inner joint cavity, it restores viscosity within the synovial fluid, improving lubrication and cushioning of the joint. Arthrosamid® also integrates into the synovium of the inner joint capsule creating a cushion-like effect.

Benefits of Arthosamid®
Because Arthrosamid® works to cushion the joint, it can reduce your pain, decrease stiffness, and help movement. It has been shown to be safe and can give long-acting relief, improving your quality of life.

Arthrosamid® is injected into the intra-articular space as a minimally invasive, out-patient procedure. You do not need to stay in hospital for treatment and clinicians are very familiar with injections into the knee joint.

Arthrosamid® is safe for intended use and is biocompatible which allows it to integrate with the tissues in your knee. The overall safety profile of the hydrogel has undergone two decades of research and development with approximately 1,000,000 hydrogel units used for various indications in the body.

In clinical trials, patients reported a reduction in their pain levels by Week 4 after their injection. The reduction in pain was sustained over 104 weeks. Arthrosamid® trials will continue to follow patients for 5 years. 

Arthrosamid® is different from viscosupplement injections such as Hyaluronic Acid (HA), Platelet Rich Plasma (PRP) and regenerative stem cell therapy. Unlike these treatments, Arthrosamid® becomes an integrated part of the soft synovial tissue in the joint capsule and may work for longer. In the clinical trials patients were still benefitting beyond 104 weeks

Before you are given an Arthrosamid® injection, you will also have a local anaesthetic, which may sting a little, to numb the area around your knee. No serious adverse events linked to Arthrosamid® have been reported in studies. The most commonly reported side effects were injection related mild to moderate pain and or joint swelling, which were generally transient in nature.